Regarding the effect of ionic silver directly on the bacteria, then on this issue there is no consensus. It is known that bacteria, the protoplasm which has a negative electrical charge and attract positively charged silver ions. In case of contact with silver ions by bacteria in the recent physiological result of exposure to the metal ions are dying.

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Some researchers have a special significance attached to physical and chemical processes occurring in the plasma of bacteria. Back in 1921 Wernicke suggested that the action of silver ions on bacteria is the oxidation of plasma oxygen dissolved in water, and money plays a catalytic role. On this basis, it can be concluded that metal ions do not act immediately, and are primarily transmitters of oxygen, the oxidation itself is in the immediate accession of oxygen, and in the dehydrogenation of compounds of the plasma.

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This view is shared by many researchers. Noteworthy Zyupfle theory according to which the antimicrobial action of silver ions is due to the adsorption of bacterial cells. Zyupfle refuted the prevailing hypothesis of Herzberg to him that the silver ions to increase the density of atomic oxygen, which then causes dehydration of bacterial cells. The experiments on the anaerobic bacteria Zyupfle showed that an increase in the density of oxygen around the cells only occurs when silver is in the form of pure metal, ie, when it is not ionized, and therefore does not have anti-microbial action.

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Developing further the theory Zyupfle, Leitner showed that the bacteria in a complex - Silver latter can be displaced by substances that have a greater affinity with the surface of bacteria. In this case the action of anti-microbial silver weakened. The degree of adsorption of silver depends on the total surface of bacteria in the water, the values ​​of their charge, as well as on pH and salt content.